Blood Viral Load (VL) Not Clinically Meaningful in Symptomatic Congenital Cytomegalovirus (cCMV) Infection
نویسندگان
چکیده
944. Perinatal Case Fatality Rate Related to Congenital Zika Syndrome in Brazil: a Cross-Sectional Study Igor Thiago Queiroz, MD, PhD; Jessika Thais Da Silva Maia, MS; Gleysson Rosa, RN, MD; Tatyana Vidal Mendes, RN; S. Jayne Alves Vidal, RN; Maria Goretti Lins, MD; Marcelo Rodrigues Zacarkim, MD, MS; David Aronoff, MD, FIDSA; A. Desiree Labeaud, MD, MS; Nilson N. Mendes Neto, MS; Universidade Potiguar, Natal, Brazil; Universidade Potiguar, Natal – RN, Brazil; Harvard Medical School, Boston, Massachusetts; Secretaria Municipal de Saude, Cajazeiras-PB, cajazeiras-PB, Brazil; SESAP – Rio Grande do Norte, Natal, Brazil; Hospital Infantil Varela Santiago, Natal, Brazil; Vanderbilt University School of Medicine, Division of Infectious Diseases, Nashville, Tennessee; Pediatric Infectious Diseases, Stanford University, Stanford, California; Extension Center, University of California, Davis, Davis, California
منابع مشابه
Symptomatic Congenital Cytomegalovirus Infection in Children of Seropositive Women
Cytomegalovirus (CMV) is the most frequent congenital virus infection worldwide. The risk of congenital CMV (cCMV) transmission is highest in seronegative women who acquire primary CMV infection during pregnancy. A growing body of evidence indicates that secondary CMV infections in pregnant women with preconceptual immunity (either through reactivation of latent virus or re-infection with a new...
متن کاملHuman cytomegalovirus UL144 is associated with viremia and infant development sequelae in congenital infection.
Human cytomegalovirus (HCMV) strains may be genotyped based on polymorphisms that exist within the UL144 gene, which is one of 19 viral genes lost in attenuated laboratory strains. In the present study, UL144 genotypes in congenitally infected babies (congenital cytomegalovirus [cCMV]) were determined, and the relationship between the genotype, viral load, cytokine profile, and patient developm...
متن کاملHepatic involvement in congenital cytomegalovirus infection - infrequent yet significant.
Congenital cytomegalovirus (cCMV) infection can reside in many organ systems; however, the virus has a particular predilection towards inhabiting the reticuloendothelial system, especially the liver. Specific studies focusing only on hepatic involvement in infants with cCMV are lacking. We report our experience with a large cohort of infants treated in our hospital clinic due to cCMV and hepati...
متن کاملEmerging (val)ganciclovir resistance during treatment of congenital CMV infection: a case report and review of the literature
BACKGROUND Congenital cytomegalovirus (cCMV) infection is an important illness that is a common cause of hearing loss in newborn infants and a major cause of disability in children. For that reason, treatment of symptomatic patients with either ganciclovir or its pro-drug valganciclovir is recommended. Treatment duration of 6 months has been shown to be more beneficial than shorter courses; how...
متن کاملPrevalence of congenital cytomegalovirus infection in symptomatic newborns under 3 weeks in Tehran, Iran
BACKGROUND Cytomegalovirus (CMV) is a common cause of congenital infection worldwide and infants with symptomatic congenital CMV (cCMV) infection are at significantly increased risk of developing adverse long-term outcomes. This study aimed to determine the prevalence of cCMV infections in symptomatic infants under 3 weeks in Tehran, IRAN and to evaluate the usefulness of serologic markers in t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 4 شماره
صفحات -
تاریخ انتشار 2017